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The Aetherochemical Research Facility

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The Aetherochemical Research Facility

The Aetherochemical Research Facility.png
60 (Sync: 60)
Item Level
142 (Sync: 180)
Party size
Light Party
4 man 1 Tank role.png 1 Healer role.png 2 DPS role.png
Time limit
90 minutes
Duty Finder
Dungeons (Heavensward)
Level 50/60/70/80 Dungeons
Allagan Tomestone of Poetics 150 
Req. quest
Main Scenario quest Heavensward
Azys Lla (X:21.4, Y:22.5, Z:8.7)
Duty Support, Explorer

Your pursuit of the archbishop has brought you to the Aetherochemical Research Facility, at the heart of the floating isle of Azys Lla. However, he and his knights are not the only threat for which you must be prepared; shortly before your arrival, the VIth Imperial Legion entered the facility in search of the secret to mastering primals, and their presence will serve to complicate matters. With multiple factions and their ambitions set on a collision course, your mission promises to be fraught with danger and uncertainty both.

— In-game description

The Aetherochemical Research Facility is a level 60 dungeon introduced in patch 3.0 with Heavensward. With the addition of Duty Support in Patch 6.3, changes to progression and bosses were implemented. Furthermore, it is the only MSQ dungeon to have 4 bosses.


  1. Clear Analysis and Proving
  2. Clear Bioweapons Research
  3. Defeat Harmachis
  4. Defeat all opposition
  5. Defeat Ascian Prime


The Aetherochemical Research Facility Guide

Aggressive difficulty r5.png Regula van Hydrus

  • Stuns the tank and follows up with a high damage attack. Heal as necessary.
  • Summons turrets every phase swap, with one additional turret per swap. Turrets self-destruct if not killed in time, causing room-wide damage.
    • Magitek Turret Is target a random party member with a visible line and will continuously attack them.
    • Magitek Turret IIs target random party members with circle AoEs.
  • After switching to Phase 2, he will move to the walls and repeatedly cast Magitek Slug, an easily dodged line AoE
  • At the end of Phase 2 will cast Magitek Spread, a large AoE that hits everywhere except a wide cone behind him.

Aggressive difficulty r5.png Harmachis

Party members should remain on different sides of the boss when possible, only stacking up to mitigate Ballistic Missile.

  • Weighing of the Heart: Changes Forms, form will be announced but may be only a split second before the change. There is no cast or announcement prior to changing back to Sphinx.
  • Sphinx form
    • Riddle of the Sphinx is an easily dodged circle AoE.
    • Will periodically attack the tank with a unmarked cone of Poison.
  • Anti-Cobra form
    • High damage tank buster (6000-8000+ damage)
  • Anti-Naga form
    • Petrifaction is a gaze attack that will cause 10 seconds of Petrification unless you are looking away from the boss.
    • Circle of Flames is an instant AoE that will target multiple party members, stay spread out to avoid stacking damage.
  • Anti-Machina form
    • Ballistic Missile will target a party member with a high-damage missile, indicated by a small circle on the ground. Have one other party member stack on you to prevent the damage. More than two people sharing the impact will not prevent the damage.
    • Gaseous Bomb is an instant cone AoE that will target a random party member.

Aggressive difficulty r6.png Lahabrea & Igeyorhm

As of Patch 6.3, the battle will only end when both Ascians' health are reduced to 0.1% instead of 50%, and both will always be targettable.

  • Shadow Flare: Unavoidable Raidwade damage cast by Lahabrea
  • Fire Sphere: Lahabrea summons five untargettable Burning Stars that will explode in AoE circles after a few seconds.
    • Esoteric Fusion: Another version of this spell will result in two pairs of Burning Stars that are tethered and advance towards each other, which will explode upon contact.
  • Grip of Night: A frontal cone AoE cast by Igeyorhm.
  • Circle of Ice: Igeyorhm summons four Frozen Stars that detonate Donut AoE circles. Stand on the Frozen Stars to avoid damage.
    • Esoteric Fusion: Igeyorhm will tether two of her Frozen Stars together, creating a bigger donut AoE that covers the safe spots in the other Frozen Stars. Players should therefore stand under where the tethered Frozen Stars will detonate to avoid damage.
  • End of Days: Similar to the Towering Oliphant's Rout attack in The Dusk Vigil, this is a line stack marker, which requires players to line up between Lahabrea and the targetted player.
  • Dark Fire II: Lahabrea puts circle purple AoE markers on all players, who should spread to avoid overlapping.
  • The Ascians will keep their health equalized throughout the fight by sacrificing some of their own HP to heal the other,

Aggressive difficulty r6.png Ascian Prime

The dungeon does not end when Lahabrea and Igeyorhm are defeated. Instead, a noteably long but skippable cutscene will show the two merging into the real final boss, an Ascian Prime.

  • Shadow Flare: Unavoidable Raidwide Damage.
  • Height of Chaos: Tankbuster
  • Dualstar: Features combinations of the tethered Burning Stars and Frozen Stars from the previous battle. Ascian Prime will then cast Fusion Prime to make them collide. Players can eye the distance of the tethers to tell which will colide first.
    • If the Frozen Stars colide first, stand under them and quickly run away from the imminent detonation of the Burning Stars
    • If the Burning Stars colide first, run away from them and then quickly run under the Frozen Stars before they detonate as well.
  • Universal Manipulation: Causes room-wide damage and five debuffs. As of Patch 6.3, there no portals to hide in and avoid this, and the debuffs will detonate the following mechanics:
    • Bleed icon1.png Bleeding: Players take damage overtime until the debuff expires.
    • Ancient circle icon1.png Ancient Circle: Upon expiring, this creates a massive donut AoE around each player. They should stack in the center to ensure the donut AoEs do not spread there.
    • Dark whispers icon1.png Dark Whispers: Upon expiring, this creates a purple AoE circle on each player, who should spread out to avoid overlapping.
    • Ancient frost icon1.png Ancient Frost: Upon expiring, the afflicted player will find themselves the victim of a stack marker.
    • Burning chains icon2.png Burning Chains: Upon expiring, players are chained by pairs and must run away from each other to break them.
  • Entropic Flame: A line stack marker.
  • Arcane Revelation: A reprisal of Lahabrea's ultimate from Main Scenario QuestThe Ultimate Weapon. Ascian Prime becomes untargettable, summons a large Arcane Sphere, and begins siphoning power from it to fill an Ascian Prime's Power gauge. Meanwhile, untargettable Shades of Lahabrea and Igeyorhm periodically appear to unleash mechanics on the party
    • Chilling Cross and Dark Fire II: Igeyorhm's shade creates cross line AoEs from the middle of the arena while Lahabrea's shade places purple AoE circles on players.
    • Dark Blizzard II and Dark Fire II: Igeyorhm's shade creates several frozen line AoEs while Lahabrea's shade places purple AoE circles on players.
    • Shadow Flare: Both Shades cast this at the same time, dealing extra raidwide damage.
    • Annihilation: Heavy raid-wide damage based on how far the Ascian Prime's Power gauge filled. If Ascian Prime was allowed to reach 100%, his attack will wipe the party
  • Ancient Eruption: Ascian Prime causes AoE circles to appear underneath each player.

From there, the mechanics repeat themselves until the boss is defeated.


Silver Coffer (small).png Regula van Hydrus

Silver Coffer (small).png Harmachis

Silver Coffer (small).png Lahabrea & Igeyorhm

Gold Coffer (small).png Ascian Prime

Name Type Rarity Quantity
Faded copy of imagination icon1.png  Faded Copy of Imagination   This item is guaranteed to drop. Orchestrion Roll ABasic 1


This duty is associated with the following achievements:

Name Points Task Reward Patch
Mapping the realm aetherochemical research facility icon1.png  Mapping the Realm: Aetherochemical Research Facility 10 Discover every location in the Aetherochemical Research Facility. - 3.0